ID   6CFSMEo-
AC   CVCL_IN62
SY   6CFSMEO
DR   Millipore; SCC157
DR   Wikidata; Q54604526
RX   PubMed=1375758;
RX   PubMed=15463957;
RX   PubMed=16037690;
CC   Sequence variation: Mutation; HGNC; 1884; CFTR; Simple; p.Gln2Ter (c.4C>T); ClinVar=VCV000053980; Zygosity=Heterozygous (PubMed=15463957; PubMed=16037690).
CC   Sequence variation: Mutation; HGNC; 1884; CFTR; Simple; p.Phe508del (c.1521_1523delCTT); ClinVar=VCV000007105; Zygosity=Heterozygous (PubMed=15463957; PubMed=16037690).
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) [Note=pSVori-].
CC   Derived from site: In situ; Lung, bronchus, submucosal gland; UBERON=UBERON_8410043.
CC   Cell type: Epithelial cell of bronchus; CL=CL_0002328.
ST   Source(s): Millipore=SCC157
ST   Amelogenin: X
ST   CSF1PO: 9,12
ST   D13S317: 12
ST   D16S539: 14
ST   D18S51: 16,20
ST   D21S11: 29,30
ST   D3S1358: 15,18
ST   D5S818: 11,12
ST   D7S820: 9
ST   D8S1179: 8,13
ST   FGA: 19
ST   Penta D: 9,10
ST   Penta E: 10,11
ST   TH01: 7,9.3
ST   TPOX: 8,11
ST   vWA: 14,17
DI   NCIt; C2975; Cystic fibrosis
DI   ORDO; Orphanet_586; Cystic fibrosis
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_VP33 ! CFSMEo-
OI   CVCL_IN60 ! 2CFSMEo-
OI   CVCL_IN58 ! 3ACFSMEo-
SX   Sex unspecified
AG   Age unspecified
CA   Transformed cell line
DT   Created: 01-12-16; Last updated: 02-05-24; Version: 14
//
RX   PubMed=1375758; DOI=10.1073/pnas.89.11.5171;
RA   Cozens A.L., Yezzi M.J., Chin L., Simon E.M., Finkbeiner W.E.,
RA   Wagner J.A., Gruenert D.C.;
RT   "Characterization of immortal cystic fibrosis tracheobronchial gland
RT   epithelial cells.";
RL   Proc. Natl. Acad. Sci. U.S.A. 89:5171-5175(1992).
//
RX   PubMed=15463957; DOI=10.1016/j.jcf.2004.05.040;
RA   Gruenert D.C., Willems M., Cassiman J.-J., Frizzell R.A.;
RT   "Established cell lines used in cystic fibrosis research.";
RL   J. Cyst. Fibros. 3:191-196(2004).
//
RX   PubMed=16037690; DOI=10.1159/000087235;
RA   da Paula A.C., Ramalho A.S., Farinha C.M., Cheung J., Maurisse R.,
RA   Gruenert D.C., Ousingsawat J., Kunzelmann K., Amaral M.D.;
RT   "Characterization of novel airway submucosal gland cell models for
RT   cystic fibrosis studies.";
RL   Cell. Physiol. Biochem. 15:251-262(2005).
//