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Cellosaurus 2CFSMEo- (CVCL_IN60)

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Cell line name 2CFSMEo-
Accession CVCL_IN60
Resource Identification Initiative To cite this cell line use: 2CFSMEo- (RRID:CVCL_IN60)
Comments Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pSVori-).
Derived from site: In situ; Lung, bronchus, submucosal gland; UBERON=UBERON_8410043.
Cell type: Epithelial cell of bronchus; CL=CL_0002328.
Sequence variations
  • Mutation; HGNC; HGNC:1884; CFTR; Simple; p.Gln2Ter (c.4C>T); ClinVar=VCV000053980; Zygosity=Heterozygous (from autologous cell lines 6CFSMEo-; CFSMEo-).
  • Mutation; HGNC; HGNC:1884; CFTR; Simple; p.Phe508del (c.1521_1523delCTT); ClinVar=VCV000007105; Zygosity=Heterozygous (from autologous cell lines 6CFSMEo-; CFSMEo-).
Disease Cystic fibrosis (NCIt: C2975)
Cystic fibrosis (ORDO: Orphanet_586)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_B4IB (2CFSMEo-/6REP-CFTR)
Originate from same individual CVCL_VP33 ! CFSMEo-
CVCL_IN58 ! 3ACFSMEo-
CVCL_IN62 ! 6CFSMEo-
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Transformed cell line
Web pages Info; Dartmouth; -; https://web.archive.org/web/20190126194809/http://www.dartmouth.edu/~cysfib/cell-lines.html
Publications

PubMed=1375758; DOI=10.1073/pnas.89.11.5171; PMCID=PMC49251
Alison L. Cozens, Michael J. Yezzi, Lynda Chin, E.M. Simon, Walter E. Finkbeiner, John A. Wagner, Dieter C. Gruenert;
Characterization of immortal cystic fibrosis tracheobronchial gland epithelial cells.
Proc. Natl. Acad. Sci. U.S.A. 89:5171-5175(1992)

Cross-references
Encyclopedic resources Wikidata; Q54584432
Entry history
Entry creation01-Dec-2016
Last entry update10-Apr-2025
Version number18