Cellosaurus logo
expasy logo

Cellosaurus Sdhb fl/fl (CVCL_HG11)

[Text version]
Cell line name Sdhb fl/fl
Accession CVCL_HG11
Resource Identification Initiative To cite this cell line use: Sdhb fl/fl (RRID:CVCL_HG11)
Comments Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6Ncr x 129S6/SvEvTac.
Hierarchy Parent: CVCL_E222 (G4 [Mouse ESC])
Children:
CVCL_HG12 (Sdhb-/- CL 5)CVCL_HG13 (Sdhb-/- CL 7)
Sex of cell Male
Age at sampling Blastocyst stage
Category Transformed cell line
Publications

PubMed=26302408; DOI=10.1038/ncb3233
Cardaci S., Zheng L., MacKay G., van den Broek N.J.F., MacKenzie E.D., Nixon C., Stevenson D., Tumanov S., Bulusu V., Kamphorst J.J., Vazquez A., Fleming S., Schiavi F., Kalna G., Blyth K., Strathdee D., Gottlieb E.
Pyruvate carboxylation enables growth of SDH-deficient cells by supporting aspartate biosynthesis.
Nat. Cell Biol. 17:1317-1326(2015)

Cross-references
Cell line collections (Providers) CancerTools; 153294
Ximbio; 153294
Encyclopedic resources Wikidata; Q54952714
Entry history
Entry creation01-Dec-2016
Last entry update29-Jun-2023
Version number7