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Cellosaurus Sdhb-/- CL 7 (CVCL_HG13)

[Text version]
Cell line name Sdhb-/- CL 7
Synonyms Sdhb -/- CL 7
Accession CVCL_HG13
Resource Identification Initiative To cite this cell line use: Sdhb-/- CL 7 (RRID:CVCL_HG13)
Comments Knockout cell: Method=Cre/loxP; MGI; MGI:1914930; Sdhb.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6Ncr x 129S6/SvEvTac.
Hierarchy Parent: CVCL_HG11 (Sdhb fl/fl)
Sex of cell Male
Age at sampling Blastocyst stage
Category Transformed cell line
Publications

PubMed=26302408; DOI=10.1038/ncb3233; PMCID=PMC4591470
Simone Cardaci, Liang Zheng, Gillian MacKay, Niels J.F. van den Broek, Elaine D. MacKenzie, Colin Nixon, David Stevenson, Sergey Tumanov, Vinay Bulusu, Jurre J. Kamphorst, Alexei Vazquez ...Show all 17 authors... , Stewart Fleming, Francesca Schiavi, Gabriela Kalna, Karen Blyth, Douglas Strathdee, Eyal Gottlieb; Show fewer authors
Pyruvate carboxylation enables growth of SDH-deficient cells by supporting aspartate biosynthesis.
Nat. Cell Biol. 17:1317-1326(2015)

Cross-references
Cell line collections (Providers) CancerTools; 153293
Ximbio; 153293
Encyclopedic resources Wikidata; Q54952717
Entry history
Entry creation01-Dec-2016
Last entry update29-Jun-2023
Version number7