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Cellosaurus Sdhb-/- CL 5 (CVCL_HG12)

[Text version]
Cell line name Sdhb-/- CL 5
Synonyms Sdhb -/- CL 5
Accession CVCL_HG12
Resource Identification Initiative To cite this cell line use: Sdhb-/- CL 5 (RRID:CVCL_HG12)
Comments Knockout cell: Method=Cre/loxP; MGI; MGI:1914930; Sdhb.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6Ncr x 129S6/SvEvTac.
Hierarchy Parent: CVCL_HG11 (Sdhb fl/fl)
Sex of cell Male
Age at sampling Blastocyst stage
Category Transformed cell line
Publications

PubMed=26302408; DOI=10.1038/ncb3233
Cardaci S., Zheng L., MacKay G., van den Broek N.J.F., MacKenzie E.D., Nixon C., Stevenson D., Tumanov S., Bulusu V., Kamphorst J.J., Vazquez A., Fleming S., Schiavi F., Kalna G., Blyth K., Strathdee D., Gottlieb E.
Pyruvate carboxylation enables growth of SDH-deficient cells by supporting aspartate biosynthesis.
Nat. Cell Biol. 17:1317-1326(2015)

Cross-references
Cell line collections CancerTools; 153292
Ximbio; 153292
Encyclopedic resources Wikidata; Q54952715
Entry history
Entry creation01-Dec-2016
Last entry update21-Mar-2023
Version number6