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Cellosaurus HepG2T14 (CVCL_HE77)

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Cell line name HepG2T14
Synonyms HepG2T-14
Accession CVCL_HE77
Resource Identification Initiative To cite this cell line use: HepG2T14 (RRID:CVCL_HE77)
Comments Population: Caucasian.
Virology: Transfected with a circular hepatitis B virus (HBV).
Transformant: NCBI_TaxID; 10407; Hepatitis B virus (HBV).
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Disease Hepatoblastoma (NCIt: C3728)
Hepatoblastoma (ORDO: Orphanet_449)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0027 (Hep-G2)
Children:
CVCL_HE78 (HepG2T14.1)
Sex of cell Male
Age at sampling 15Y
Category Cancer cell line
Publications

PubMed=3019565; DOI=10.1016/0092-8674(86)90364-8
Camille Sureau, Jean-Loup Romet-Lemonne, James I. Mullins, Myron Elmer Essex;
Production of hepatitis B virus by a differentiated human hepatoma cell line after transfection with cloned circular HBV DNA.
Cell 47:37-47(1986)

PubMed=9755253; DOI=10.1002/hep.510280431
Philippe Roingeard, Camille Sureau;
Ultrastructural analysis of hepatitis B virus in HepG2-transfected cells with special emphasis on subviral filament morphogenesis.
Hepatology 28:1128-1133(1998)

Cross-references
Cell line databases/resources cancercelllines; CVCL_HE77
Encyclopedic resources Wikidata; Q54882864
Entry history
Entry creation01-Dec-2016
Last entry update19-Dec-2024
Version number15