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Cellosaurus HepG2T14.1 (CVCL_HE78)

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Cell line name HepG2T14.1
Accession CVCL_HE78
Resource Identification Initiative To cite this cell line use: HepG2T14.1 (RRID:CVCL_HE78)
Comments Population: Caucasian.
Virology: Transfected with a circular hepatitis B virus (HBV).
Karyotypic information: Has lost chromosome Y.
Transformant: NCBI_TaxID; 10407; Hepatitis B virus (HBV).
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Disease Hepatoblastoma (NCIt: C3728)
Hepatoblastoma (ORDO: Orphanet_449)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_HE77 (HepG2T14)
Sex of cell Male
Age at sampling 15Y
Category Cancer cell line
Publications

PubMed=9247614; DOI=10.1016/S0027-5107(97)00068-7
Kristin W. Livezey, Daniela Simon;
Accumulation of genetic alterations in a human hepatoma cell line transfected with hepatitis B virus.
Mutat. Res. 377:187-198(1997)

Cross-references
Cell line databases/resources cancercelllines; CVCL_HE78
Encyclopedic resources Wikidata; Q54882865
Entry history
Entry creation01-Dec-2016
Last entry update19-Dec-2024
Version number15