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Cellosaurus 1321N1/P2Y12/Galpha15 (CVCL_H357)

[Text version]
Cell line name 1321N1/P2Y12/Galpha15
Accession CVCL_H357
Resource Identification Initiative To cite this cell line use: 1321N1/P2Y12/Galpha15 (RRID:CVCL_H357)
Comments Problematic cell line: Contaminated. Ancestral cell line (U-118MG) has been shown to be a U-138MG derivative.
Population: Caucasian.
Transfected with: HGNC; 4383; GNA15.
Transfected with: HGNC; 18124; P2RY12.
Derived from sampling site: Brain.
Sequence variations
  • Mutation; HGNC; 9588; PTEN; Simple; c.1026+1G>T (IVS8+1G>T); ClinVar=VCV000635377; Zygosity=Homozygous; Note=Splice donor mutation (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg213Gln (c.638G>A); ClinVar=VCV000135359; Zygosity=Homozygous (from parent cell line).
Disease Astrocytoma (NCIt: C60781)
Astrocytoma (ORDO: Orphanet_94)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0110 (1321N1)
Sex of cell Male
Age at sampling 47Y
Category Cancer cell line
Web pages https://www.genscript.com/molecule/M00261-P2Y12.html
Cross-references
Encyclopedic resources Wikidata; Q54581495
Entry history
Entry creation11-Feb-2013
Last entry update21-Mar-2023
Version number18