ID   1321N1/P2Y12/Galpha15
AC   CVCL_H357
DR   cancercelllines; CVCL_H357
DR   GenScript; M00261
DR   Wikidata; Q54581495
CC   Problematic cell line: Contaminated. Ancestral cell line (U-118MG) has been shown to be a U-138MG derivative.
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; HGNC:9588; PTEN; Simple; c.1026+1G>T (IVS8+1G>T); ClinVar=VCV000635377; Zygosity=Homozygous; Note=Splice donor mutation (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg213Gln (c.638G>A); ClinVar=VCV000135359; Zygosity=Homozygous (from parent cell line).
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:4383; GNA15.
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:18124; P2RY12.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR).
CC   Derived from site: In situ; Brain; UBERON=UBERON_0000955.
DI   NCIt; C60781; Astrocytoma
DI   ORDO; Orphanet_94; Astrocytoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0110 ! 1321N1
SX   Male
AG   47Y
CA   Cancer cell line
DT   Created: 11-02-13; Last updated: 10-04-25; Version: 23
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