Cellosaurus logo
expasy logo

Cellosaurus EDITGENE U-937-FLUC (CVCL_F5U4)

[Text][XML][JSON]
Cell line name EDITGENE U-937-FLUC
Synonyms U-937-FLUC
Accession CVCL_F5U4
Resource Identification Initiative To cite this cell line use: EDITGENE U-937-FLUC (RRID:CVCL_F5U4)
Comments Population: Caucasian.
Characteristics: Growth mode Suspension.
Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase (Note=With optimized codon usage for mammalian expression = Luc2).
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene fusion; HGNC; HGNC:16063; MLLT10 + HGNC; HGNC:15514; PICALM; Name(s)=PICALM-MLLT10, CALM-AF10 (from parent cell line).
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Gly129fs*51 (c.387_388insCGCC); Zygosity=Hemizygous (from parent cell line).
  • Mutation; HGNC; HGNC:9644; PTPN11; Simple; p.Gly60Arg (c.178G>C); ClinVar=VCV000372590; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; c.559+1G>A (p.Val173Trpfs*59); ClinVar=VCV000428908; Zygosity=Homozygous; Note=Splice donor mutation (from parent cell line).
  • Mutation; HGNC; HGNC:12796; WT1; Simple; p.Arg301Ter (c.901C>T) (p.Arg352Ter, c.1054C>T) (p.Arg374Ter, c.1120C>T); ClinVar=VCV000449416; Zygosity=Heterozygous (from parent cell line).
Disease Adult acute monocytic leukemia (NCIt: C8263)
Acute monoblastic/monocytic leukemia (ORDO: Orphanet_514)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0007 (U-937)
Sex of cell Male
Age at sampling 37Y
Category Cancer cell line
STR profile Source(s): EDITGENE=EDC01375

Markers:
AmelogeninX
CSF1PO12
D2S44110
D2S133817,20
D3S135816
D5S81812
D7S8209,11
D8S117912,13
D12S39117,18
D13S31710,12
D16S53912
D18S5113,14
D19S43314,16
D21S1127,29
FGA22,24,25
Penta D12,13
Penta E13
TH016,9.3
TPOX8,11
vWA14,15

Run an STR similarity search on this cell line
Cross-references
Cell line collections (Providers) EDITGENE; EDC01375
Entry history
Entry creation25-Jun-2026
Last entry update25-Jun-2026
Version number1