ID   EDITGENE U-937-FLUC
AC   CVCL_F5U4
SY   U-937-FLUC
DR   EDITGENE; EDC01375
CC   Population: Caucasian.
CC   Characteristics: Growth mode Suspension.
CC   Sequence variation: Gene fusion; HGNC; HGNC:16063; MLLT10 + HGNC; HGNC:15514; PICALM; Name(s)=PICALM-MLLT10, CALM-AF10 (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Gly129fs*51 (c.387_388insCGCC); Zygosity=Hemizygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:9644; PTPN11; Simple; p.Gly60Arg (c.178G>C); ClinVar=VCV000372590; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; c.559+1G>A (p.Val173Trpfs*59); ClinVar=VCV000428908; Zygosity=Homozygous; Note=Splice donor mutation (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:12796; WT1; Simple; p.Arg301Ter (c.901C>T) (p.Arg352Ter, c.1054C>T) (p.Arg374Ter, c.1120C>T); ClinVar=VCV000449416; Zygosity=Heterozygous (from parent cell line).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase (Note=With optimized codon usage for mammalian expression = Luc2).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
CC   Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
ST   Source(s): EDITGENE=EDC01375
ST   Amelogenin: X
ST   CSF1PO: 12
ST   D12S391: 17,18
ST   D13S317: 10,12
ST   D16S539: 12
ST   D18S51: 13,14
ST   D19S433: 14,16
ST   D21S11: 27,29
ST   D2S1338: 17,20
ST   D2S441: 10
ST   D3S1358: 16
ST   D5S818: 12
ST   D7S820: 9,11
ST   D8S1179: 12,13
ST   FGA: 22,24,25
ST   Penta D: 12,13
ST   Penta E: 13
ST   TH01: 6,9.3
ST   TPOX: 8,11
ST   vWA: 14,15
DI   NCIt; C8263; Adult acute monocytic leukemia
DI   ORDO; Orphanet_514; Acute monoblastic/monocytic leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0007 ! U-937
SX   Male
AG   37Y
CA   Cancer cell line
DT   Created: 25-06-26; Last updated: 25-06-26; Version: 1
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