Cellosaurus cell line EDITGENE ASXL1 Knockout OCI-AML3 Cell Line (CVCL

Cross-references
Cell line name	EDITGENE ASXL1 Knockout OCI-AML3 Cell Line
Synonyms	ASXL1 Knockout OCI-AML3 Cell Line
Accession	CVCL_F5IN
Resource Identification Initiative	To cite this cell line use: EDITGENE ASXL1 Knockout OCI-AML3 Cell Line (RRID:CVCL_F5IN)
Comments	Population: Caucasian. Characteristics: Growth mode Suspension. Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:18318; ASXL1. Genetic integration: Method=CRISPR/Cas9; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR). Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations	Mutation; HGNC; HGNC:2978; DNMT3A; Simple; p.Arg882Cys (c.2644C>T); ClinVar=VCV000375882; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:7910; NPM1; Simple; p.Trp288Cysfs*12 (c.860_863dupTCTG); ClinVar=VCV000013998; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Homozygous (from parent cell line).
Disease	Adult acute myelomonocytic leukemia (NCIt: C7962) Acute myelomonocytic leukemia (ORDO: Orphanet_517)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_1844 (OCI-AML-3)
Sex of cell	Male
Age at sampling	57Y
Category	Cancer cell line
Cell line collections (Providers)	EDITGENE; EDC07928
Entry history
Entry creation	25-Jun-2026
Last entry update	25-Jun-2026
Version number	1