ID   EDITGENE ASXL1 Knockout OCI-AML3 Cell Line
AC   CVCL_F5IN
SY   ASXL1 Knockout OCI-AML3 Cell Line
DR   EDITGENE; EDC07928
CC   Population: Caucasian.
CC   Characteristics: Growth mode Suspension.
CC   Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:18318; ASXL1.
CC   Sequence variation: Mutation; HGNC; HGNC:2978; DNMT3A; Simple; p.Arg882Cys (c.2644C>T); ClinVar=VCV000375882; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:7910; NPM1; Simple; p.Trp288Cysfs*12 (c.860_863dupTCTG); ClinVar=VCV000013998; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Homozygous (from parent cell line).
CC   Genetic integration: Method=CRISPR/Cas9; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
DI   NCIt; C7962; Adult acute myelomonocytic leukemia
DI   ORDO; Orphanet_517; Acute myelomonocytic leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1844 ! OCI-AML-3
SX   Male
AG   57Y
CA   Cancer cell line
DT   Created: 25-06-26; Last updated: 25-06-26; Version: 1
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