Cellosaurus HeLa TRIP13 KO: auxin-inducible degron (AID)-TRIP13-Tet-Off. (CVCL_F4BW)
| Cell line name | HeLa TRIP13 KO: auxin-inducible degron (AID)-TRIP13-Tet-Off. |
|---|---|
| Synonyms | TRIP13 KO:AID; Clone 9; TRIP13KO AID-TRIP13 |
| Accession | CVCL_F4BW |
| Resource Identification Initiative | To cite this cell line use: HeLa TRIP13 KO: auxin-inducible degron (AID)-TRIP13-Tet-Off. (RRID:CVCL_F4BW) |
| Comments | Population: African American. Characteristics: Expresses AID-TRIP13 under the control of a Tet-Off promoter in TRIP13 knockout background. Expression of AID-TRIP13 is suppress by doxycycline and indole-3-acetic acid (IAA). Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:12307; TRIP13. Genetic integration: Method=Transduction; Gene=HGNC; HGNC:12307; TRIP13 (Note=With a N-ter AID tag). Genetic integration: Method=Transduction; Gene=UniProtKB; P93830; Arabidopsis thaliana IAA17 (Note=acts as an auxin-inducible degron (AID)). Genetic integration: Method=Transduction; Gene=UniProtKB; Q570C0; Arabidopsis thaliana TIR1 (Note=With a Myc tag). Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR). Genetic integration: Method=Transfection; Gene=UniProtKB; P04483; Escherichia coli Tn10 tetR. Genetic integration: Method=Transfection; Gene=UniProtKB; P06492; Human herpesvirus 1 (HHV-1) VP16 (UL28) (Note=With p.Met1_Arg360del). Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo. Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18). Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002. |
| Disease | Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677) |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_2523 (HtTA-1) |
| Sex of cell | Female |
| Age at sampling | 30Y6M |
| Category | Cancer cell line |
| Publications | PubMed=29425500; DOI=10.1016/j.celrep.2018.01.027 |
| Entry history | |
| Entry creation | 25-Jun-2026 |
| Last entry update | 25-Jun-2026 |
| Version number | 1 |