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Cellosaurus HtTA-1 (CVCL_2523)

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Cell line name HtTA-1
Synonyms HtTA1
Accession CVCL_2523
Resource Identification Initiative To cite this cell line use: HtTA-1 (RRID:CVCL_2523)
Comments Population: African American.
Characteristics: Transfected with the tetracycline transactivator (tTA) protein, a fusion of tetR with the activation domain of HSV-1 VP16.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P04483; Escherichia coli Tn10 tetR.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P06492; Human herpesvirus 1 (HHV-1) VP16 (UL28) (Note=With p.Met1_Arg360del).
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Children:
CVCL_1H05 (Clone 69T1RevEnv)CVCL_1H06 (Clone HXBdeltaPdeltaEnv-T1RevEnv)CVCL_2768 (X1/5)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
Publications

PubMed=1319065; DOI=10.1073/pnas.89.12.5547; PMCID=PMC49329
Manfred Gossen, Hermann Bujard;
Tight control of gene expression in mammalian cells by tetracycline-responsive promoters.
Proc. Natl. Acad. Sci. U.S.A. 89:5547-5551(1992)

Cross-references
Cell line collections (Providers) ECACC; 95091410
Cell line databases/resources CLO; CLO_0004293
CLDB; cl1767
Encyclopedic resources Wikidata; Q54896680
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number18