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Cellosaurus LRRK2 G2019S RAW 264.7 (CVCL_F1ZX)

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Cell line name LRRK2 G2019S RAW 264.7
Synonyms LRRK2G2019S macrophages
Accession CVCL_F1ZX
Resource Identification Initiative To cite this cell line use: LRRK2 G2019S RAW 264.7 (RRID:CVCL_F1ZX)
Comments Transformant: NCBI_TaxID; 11788; Abelson mouse leukemia virus (AbMuLV).
Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
Cell type: Macrophage; CL=CL_0000235.
Sequence variations
Disease Mouse leukemia (NCIt: C21604)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: BALB/c.
Hierarchy Parent: CVCL_0493 (RAW 264.7)
Children:
CVCL_F2A1 (mCherry-FTL LRRK2 G2019S RAW 264.7)CVCL_F2A3 (mCherry-NCOA4 LRRK2 G2019S RAW 264.7)CVCL_F2A5 (TMEM192-HA LRRK2 G2019S RAW 264.7)
Sex of cell Male
Age at sampling Adult
Category Cancer cell line
Publications

DOI=10.1101/2025.08.25.672135
Andres Goldman, Mai Nguyen, Joel Lanoix, Ahmed Fahmy, Yong Zhong Xu, Erwin Schurr, Pierre Thibault, Michel Desjardins, Heidi M. McBride;
LRRK2G2019S acts as a dominant interfering mutant in the context of iron overload.
bioRxiv 2025:08.25.672135-08.25.672135(2025)

Entry history
Entry creation31-Mar-2026
Last entry update31-Mar-2026
Version number1