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Cellosaurus (CVCL_F0TU)

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Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI_78543; Ponatinib (AP24534; Iclusig).
Miscellaneous: Cell line is no longer available (personal communication of Dowding, Charles).
Discontinued: ChemoScreen; Catalog number 10010C.
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 14 fused to ABL1 exon 2 (b3a2 transcript) (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gln136fs*13 (c.406_407insC); Zygosity=Homozygous (from parent cell line).
Disease Blast phase chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C9110)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0004 (K-562)
Sex of cell Female
Age at sampling 53Y
Category Cancer cell line
Entry history
Entry creation14-Dec-2015
Last entry update10-Apr-2025
Version number17