ID   L-BGH-4-3
AC   CVCL_F0TU
RX   Patent=US4686098;
RX   PubMed=2982557;
CC   Group: Patented cell line.
CC   Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-8537.
CC   Characteristics: Co-transfected with pBGH-4 plasmid that contains bovine GH1 under the control of the RSV LTR and pTK with HSV-1 TK (PubMed=2982557).
CC   Selected for resistance to: ChEBI; CHEBI_472552; 5-bromo-2'-deoxyuridine (Bromodeoxyuridine; BrdU; BUdR).
CC   Selected for resistance to: ChEBI; CHEBI_77751; 8-azaadenine.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P01246; Bovine GH1.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; Q9QNF7; Human herpesvirus 1 TK.
CC   Derived from site: In situ; Connective tissue; UBERON=UBERON_0002384.
CC   Cell type: Fibroblast; CL=CL_0000057.
CC   Breed/subspecies: C3H/An.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_0P16 ! L-M(TK-,APRT-)
SX   Male
AG   100D
CA   Spontaneously immortalized cell line
DT   Created: 27-11-25; Last updated: 27-11-25; Version: 1
//
RX   PubMed=2982557; DOI=10.1089/dna.1985.4.23;
RA   Kopchick, John Joseph
RA   Malavarca, Richard Harold
RA   Livelli, Thomas J.
RA   Leung, Frederick Chi-Ching
RT   "Use of avian retroviral-bovine growth hormone DNA recombinants to
RT   direct expression of biologically active growth hormone by cultured
RT   fibroblasts.";
RL   DNA 4:23-31(1985).
//
RX   Patent=US4686098;
RA   Kopchick, John Joseph
RA   Leung, Frederick Chi-Ching
RA   Livelli, Thomas J.
RA   Malavarca, Richard Harold
RT   "Encapsulated mouse cells transformed with avian retrovirus-bovine
RT   growth hormone DNA, and a method of administering BGH in vivo.";
RL   Patent number US4686098, 11-Aug-1987.
//