Cellosaurus cell line Hep-G2 GPC3 KO (CVCL

Cellosaurus Hep-G2 GPC3 KO (CVCL_F0T3)

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Cell line name

Hep-G2 GPC3 KO

Accession

CVCL_F0T3

Resource Identification Initiative

To cite this cell line use: Hep-G2 GPC3 KO (RRID:CVCL_F0T3)

Comments

Population: Caucasian.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:4451; GPC3.
Miscellaneous: Cell line information from personal communication of Fayn, Stanley.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.

Sequence variations

Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).

Disease

Hepatoblastoma (NCIt: C3728)
Hepatoblastoma (ORDO: Orphanet_449)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Parent: CVCL_0027 (Hep-G2)
Children:

CVCL_F6LC (HepG2/Luc GPC3-)

Sex of cell

Male

Age at sampling

15Y