| Cell line name |
AGS-4 |
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| Accession |
CVCL_F0QR |
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| Resource Identification Initiative |
To cite this cell line use: AGS-4 (RRID:CVCL_F0QR) |
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| Comments |
Population: Caucasian.
Doubling time: 28 hours (PubMed=6831414).
Derived from site: In situ; Stomach; UBERON=UBERON_0000945. |
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| Sequence variations |
- Mutation; HGNC; HGNC:2514; CTNNB1; Simple; p.Gly34Glu (c.101G>A); ClinVar=VCV000017584; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu453Lys (c.1357G>A); ClinVar=VCV000376470; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Ala (c.1634A>C); ClinVar=VCV000013659; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:667; RHOA; Simple; p.Glu64del (c.192_194del); Zygosity=Heterozygous (from parent cell line).
|
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| Disease |
Gastric adenocarcinoma (NCIt: C4004) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Hierarchy |
Parent: CVCL_0139 (AGS) |
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| Sex of cell |
Female |
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| Age at sampling |
54Y |
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| Category |
Cancer cell line |
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| Publications | PubMed=6678861; DOI=10.1007/BF00172070
Sam Christopher Barranco, Courtney M. Townsend Jr., M.A. Quraishi, N.L. Burger, H.C. Nevill, K.H. Howell, William Robert Boerwinkle;
Heterogeneous responses of an in vitro model of human stomach cancer to anticancer drugs.
Invest. New Drugs 1:117-127(1983) PubMed=6831414
Sam Christopher Barranco, Courtney M. Townsend Jr., Cacilda Casartelli, Barbara Gail Macik, N.L. Burger, William Robert Boerwinkle, William Kneff Gourley;
Establishment and characterization of an in vitro model system for human adenocarcinoma of the stomach.
Cancer Res. 43:1703-1709(1983) |
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| Entry history |
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| Entry creation | 27-Nov-2025 |
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| Last entry update | 27-Nov-2025 |
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| Version number | 1 |
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