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Cellosaurus MBU-T (CVCL_EG13)

[Text version]
Cell line name MBU-T
Accession CVCL_EG13
Resource Identification Initiative To cite this cell line use: MBU-T (RRID:CVCL_EG13)
Comments Doubling time: ~50-60 hours (DSMZ=ACC-799).
Genetic integration: Method=Transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:5173; HRAS (Note=With p.Gly12Val).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; SV40 large T antigen.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Foreskin, skin, epidermis; UBERON=UBERON_0001471+UBERON_0001003.
Cell type: Keratinocyte; CL=CL_0000312.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_EG12 (MBU-IM)
Children:
CVCL_EG14 (MBU-Ts1)CVCL_EG15 (MBU-Ts4)
Sex of cell Male
Age at sampling <1D
Category Transformed cell line
STR profile Source(s): DSMZ=ACC-799

Markers:
AmelogeninX,Y
CSF1PO10,11
D2S133824
D3S135816,17
D5S81810,12
D7S8208,11
D8S117912,13
D13S3178,11
D16S53911,12
D18S5113,15
D19S43313,14
D21S1129,34
FGA20,22
Penta D9,14
Penta E10,14
TH018,9.3
TPOX8
vWA13,15

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Publications

PubMed=27074337; DOI=10.1002/ijc.30139
Cantarino N., Fernandez-Figueras M.T., Valero V., Musulen E., Malinverni R., Granada I., Goldie S.J., Martin-Caballero J., Douet J., Forcales S.-V., Buschbeck M.
A cellular model reflecting the phenotypic heterogeneity of mutant HRAS driven squamous cell carcinoma.
Int. J. Cancer 139:1106-1116(2016)

Cross-references
Cell line collections (Providers) DSMZ; ACC-799
Cell line databases/resources DSMZCellDive; ACC-799
Encyclopedic resources Wikidata; Q54904160
Gene expression databases GEO; GSM1687265
GEO; GSM1687266
GEO; GSM1687267
GEO; GSM1687268
Entry history
Entry creation13-Jul-2016
Last entry update10-Apr-2025
Version number14