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Cellosaurus MBU-IM (CVCL_EG12)

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Cell line name MBU-IM
Accession CVCL_EG12
Resource Identification Initiative To cite this cell line use: MBU-IM (RRID:CVCL_EG12)
Comments Doubling time: ~50-60 hours (DSMZ=ACC-796).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Foreskin, skin, epidermis; UBERON=UBERON_0001471+UBERON_0001003.
Cell type: Keratinocyte; CL=CL_0000312.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_EG13 (MBU-T)
Sex of cell Male
Age at sampling <1D
Category Transformed cell line
STR profile Source(s): DSMZ=ACC-796

Markers:
AmelogeninX,Y
CSF1PO10,11
D2S133824
D3S135816,17
D5S81810,12
D7S8208,11
D8S117912,13
D13S3178,11
D16S53911,12
D18S5113,15
D19S43313,14
D21S1129,34
FGA20,22
Penta D9,14
Penta E10,14
TH018,9.3
TPOX8
vWA13,15

Run an STR similarity search on this cell line
Publications

PubMed=27074337; DOI=10.1002/ijc.30139
Neus Cantarino, Maite Teresa Fernandez-Figueras, Vanesa Valero, Eva Musulen, Roberto Malinverni, Isabel Granada, Stephen J. Goldie, Juan Martin-Caballero, Julien Douet, Sonia-Vanina Forcales, Marcus Buschbeck;
A cellular model reflecting the phenotypic heterogeneity of mutant HRAS driven squamous cell carcinoma.
Int. J. Cancer 139:1106-1116(2016)

Cross-references
Cell line collections (Providers) DSMZ; ACC-796
Cell line databases/resources DSMZCellDive; ACC-796
Encyclopedic resources Wikidata; Q54904158
Gene expression databases GEO; GSM1687261
GEO; GSM1687262
GEO; GSM1687263
GEO; GSM1687264
Entry history
Entry creation13-Jul-2016
Last entry update14-Aug-2025
Version number14