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Cellosaurus K1735-Xmet-21 (CVCL_E7ZG)

[Text version]
Cell line name K1735-Xmet-21
Synonyms K-1735-Xmet-21; X-21
Accession CVCL_E7ZG
Resource Identification Initiative To cite this cell line use: K1735-Xmet-21 (RRID:CVCL_E7ZG)
Comments Characteristics: Highly tumorigenic and metastatic. The parent cell line was X-ray irradiated (650 Rad) then implanted into the footpads of syngeneic mice. When the resulting The cell line was established from well-isolated solitary spontaneous pulmonary metastases (PubMed=3756870).
Transformant: NCIt; C17231; Ultraviolet radiation.
Transformant: NCIt; C17262; X-Ray.
Sequence variations
  • Mutation; MGI; MGI:97376; Nras; Simple; p.Gly13Asp (c.38G>A); Zygosity=Unspecified (from parent cell line).
Disease Mouse melanoma (NCIt: C21790)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C3H/HeN.
Hierarchy Parent: CVCL_F684 (K1735-M2)
Category Cancer cell line
Publications

PubMed=3756870
Fidler I.J., Talmadge J.E.
Evidence that intravenously derived murine pulmonary melanoma metastases can originate from the expansion of a single tumor cell.
Cancer Res. 46:5167-5171(1986)

Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1