ID   K1735-Xmet-21
AC   CVCL_E7ZG
SY   K-1735-Xmet-21; X-21
RX   PubMed=3756870;
CC   Characteristics: Highly tumorigenic and metastatic. The parent cell line was X-ray irradiated (650 Rad) then implanted into the footpads of syngeneic mice. When the resulting The cell line was established from well-isolated solitary spontaneous pulmonary metastases (PubMed=3756870).
CC   Sequence variation: Mutation; MGI; MGI:97376; Nras; Simple; p.Gly13Asp (c.38G>A); Zygosity=Unspecified (from parent cell line).
CC   Transformant: NCIt; C17231; Ultraviolet radiation.
CC   Transformant: NCIt; C17262; X-Ray.
CC   Breed/subspecies: C3H/HeN.
DI   NCIt; C21790; Mouse melanoma
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_F684 ! K1735-M2
CA   Cancer cell line
DT   Created: 10-04-25; Last updated: 10-04-25; Version: 1
//
RX   PubMed=3756870;
RA   Fidler I.J., Talmadge J.E.;
RT   "Evidence that intravenously derived murine pulmonary melanoma
RT   metastases can originate from the expansion of a single tumor cell.";
RL   Cancer Res. 46:5167-5171(1986).
//