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Cellosaurus PC9 fat-1 (CVCL_E6ZD)

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Cell line name PC9 fat-1
Synonyms f-PC9
Accession CVCL_E6ZD
Resource Identification Initiative To cite this cell line use: PC9 fat-1 (RRID:CVCL_E6ZD)
Comments Population: Chinese; Han and Japanese.
Characteristics: Applicable for studies investigating the effects of endogenous omega3-polyunsaturated fatty acids (ABM=T6263).
Doubling time: 18-26 hours (ABM=T6263).
Genetic integration: Method=Transfection; Gene=UniProtKB; Q9NEQ0; Caenorhabditis elegans omega-3 fatty acid desaturase fat-1.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Sequence variations
  • Mutation; HGNC; HGNC:3236; EGFR; Simple; p.Glu746_Ala750del (c.2235_2249del15); ClinVar=VCV000163343; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_B260 (PC-9)
Sex of cell Male
Age at sampling 45Y
Category Cancer cell line
Publications

DOI=10.1158/1538-7445.AM2016-4651
Soyeon Jeong, Kai-Peng Jing, Soyeon Shin, Soyeon Kim, Young-Joo Jeon, Jun-Young Heo, Gi Ryang Kweon, Seung-Kiel Park, Jong-Il Park, Kyu Lim;
Docosahexaenoic acid-induced degradation of epidermal growth factor receptor through lysosome and ubiquitin/proteasomal system in human non-small cell lung cancer cells.
Cancer Res. 76 Suppl. 14:4651-4651(2016)

Cross-references
Cell line collections (Providers) ABM; T6263
Entry history
Entry creation10-Apr-2025
Last entry update14-Aug-2025
Version number2