ID   PC9 fat-1
AC   CVCL_E6ZD
SY   f-PC9
DR   ABM; T6263
RX   DOI=10.1158/1538-7445.AM2016-4651;
CC   Population: Chinese; Han and Japanese.
CC   Characteristics: Applicable for studies investigating the effects of endogenous omega3-polyunsaturated fatty acids (ABM=T6263).
CC   Doubling time: 18-26 hours (ABM=T6263).
CC   Sequence variation: Mutation; HGNC; HGNC:3236; EGFR; Simple; p.Glu746_Ala750del (c.2235_2249del15); ClinVar=VCV000163343; Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Homozygous (from parent cell line).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; Q9NEQ0; Caenorhabditis elegans omega-3 fatty acid desaturase fat-1.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
DI   NCIt; C3512; Lung adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_B260 ! PC-9
SX   Male
AG   45Y
CA   Cancer cell line
DT   Created: 10-04-25; Last updated: 10-04-25; Version: 1
//
RX   DOI=10.1158/1538-7445.AM2016-4651;
RA   Jeong S., Jing K.-P., Shin S., Kim S., Jeon Y.-J., Heo J.-Y.,
RA   Kweon G.R., Park S.-K., Park J.-I., Lim K.;
RT   "Docosahexaenoic acid-induced degradation of epidermal growth factor
RT   receptor through lysosome and ubiquitin/proteasomal system in human
RT   non-small cell lung cancer cells.";
RL   Cancer Res. 76 Suppl. 14:4651-4651(2016).
//