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Cellosaurus FRTL-5 H-RAS(V12) clone V29 (CVCL_E5TY)

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Cell line name FRTL-5 H-RAS(V12) clone V29
Synonyms V29; FRTL5-Ras-V29; FRTL5-Ras clone V29; FRTL5-Ras
Accession CVCL_E5TY
Resource Identification Initiative To cite this cell line use: FRTL-5 H-RAS(V12) clone V29 (RRID:CVCL_E5TY)
Comments Genetic integration: Method=Transduction; Gene=HGNC; HGNC:5173; HRAS (Note=With p.Gly12Val).
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Derived from site: In situ; Thyroid gland; UBERON=UBERON_0002046.
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Fischer 344; RS=RS_0000215.
Hierarchy Parent: CVCL_0265 (FRTL-5)
Children:
CVCL_E5UE (FRTL5-Ras-Backbone Vector clone 8)CVCL_E5UF (FRTL5-Ras-Backbone Vector clone 9)CVCL_E5UG (FRTL5-Ras-Backbone Vector clone MP)
CVCL_E5UB (FRTL5-Ras-PATZ1 clone 22)CVCL_E5UC (FRTL5-Ras-PATZ1 clone 28)CVCL_E5UD (FRTL5-Ras-PATZ1 clone 33)
Sex of cell Sex unspecified
Age at sampling 6W
Category Spontaneously immortalized cell line
Publications

PubMed=15388794; DOI=10.1210/me.2004-0172
De Vita G., Bauer L., Correa da Costa V.M., De Felice M., Baratta M.G., De Menna M., Di Lauro R.
Dose-dependent inhibition of thyroid differentiation by RAS oncogenes.
Mol. Endocrinol. 19:76-89(2005)

PubMed=27125250; DOI=10.1038/srep25268; PMCID=PMC4850481
Vitiello M., Valentino T., De Menna M., Crescenzi E., Francesca P., Rea D., Arra C., Fusco A., De Vita G., Cerchia L., Fedele M.
PATZ1 is a target of miR-29b that is induced by Ha-Ras oncogene in rat thyroid cells.
Sci. Rep. 6:25268.1-25268.10(2016)

Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1