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Cellosaurus FRTL5-Ras-Backbone Vector clone MP (CVCL_E5UG)

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Cell line name FRTL5-Ras-Backbone Vector clone MP
Synonyms FR-BVMP; BVMP
Accession CVCL_E5UG
Resource Identification Initiative To cite this cell line use: FRTL5-Ras-Backbone Vector clone MP (RRID:CVCL_E5UG)
Comments Characteristics: Control cell line for the FRTL5-Ras-PATZ1 cell lines (PubMed=27125250).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:5173; HRAS (Note=With p.Gly12Val).
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Thyroid gland; UBERON=UBERON_0002046.
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Fischer 344; RS=RS_0000215.
Hierarchy Parent: CVCL_E5TY (FRTL-5 H-RAS(V12) clone V29)
Sex of cell Sex unspecified
Age at sampling 6W
Category Spontaneously immortalized cell line
Publications

PubMed=27125250; DOI=10.1038/srep25268; PMCID=PMC4850481
Vitiello M., Valentino T., De Menna M., Crescenzi E., Francesca P., Rea D., Arra C., Fusco A., De Vita G., Cerchia L., Fedele M.
PATZ1 is a target of miR-29b that is induced by Ha-Ras oncogene in rat thyroid cells.
Sci. Rep. 6:25268.1-25268.10(2016)

PubMed=30744101; DOI=10.3390/genes10020127; PMCID=PMC6410289
Vitiello M., Palma G., Monaco M., Bello A.M., Camorani S., Francesca P., Rea D., Barbieri A., Chiappetta G., De Vita G., Cerchia L., Arra C., Fedele M.
Dual oncogenic/anti-oncogenic role of PATZ1 in FRTL5 rat thyroid cells transformed by the Ha-Ras V12 oncogene.
Genes (Basel) 10:127.1-127.13(2019)

Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1