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Cellosaurus ZR-75-1 HygroR clone ZH3D7 (CVCL_E4X2)

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Cell line name ZR-75-1 HygroR clone ZH3D7
Synonyms ZR-75-1 HygroR [ZH3D7]
Accession CVCL_E4X2
Resource Identification Initiative To cite this cell line use: ZR-75-1 HygroR clone ZH3D7 (RRID:CVCL_E4X2)
Comments Population: Caucasian.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations
  • Mutation; HGNC; HGNC:5173; HRAS; Simple; p.Glu162Lys (c.484G>A); ClinVar=VCV001034833; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Leu108Arg (c.323T>G); Zygosity=Homozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0588 (ZR-75-1)
Sex of cell Female
Age at sampling 63Y
Category Cancer cell line
Publications

PubMed=9259413; DOI=10.1002/(SICI)1097-0215(19970807)72:4<700::AID-IJC24>3.0.CO;2-D
Lambert C.J. Dorssers, Jos Willibrordus Veldscholte;
Identification of a novel breast-cancer-anti-estrogen-resistance (BCAR2) locus by cell-fusion-mediated gene transfer in human breast-cancer cells.
Int. J. Cancer 72:700-705(1997)

Cross-references
Cell line collections (Providers) CancerTools; 154620
Entry history
Entry creation19-Dec-2024
Last entry update10-Apr-2025
Version number2