ID   ZR-75-1 HygroR clone ZH3D7
AC   CVCL_E4X2
SY   ZR-75-1 HygroR [ZH3D7]
DR   CancerTools; 154620
RX   PubMed=9259413;
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; HGNC:5173; HRAS; Simple; p.Glu162Lys (c.484G>A); ClinVar=VCV001034833; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Leu108Arg (c.323T>G); Zygosity=Homozygous (from parent cell line).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
DI   NCIt; C4194; Invasive breast carcinoma of no special type
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0588 ! ZR-75-1
SX   Female
AG   63Y
CA   Cancer cell line
DT   Created: 19-12-24; Last updated: 10-04-25; Version: 2
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RX   PubMed=9259413; DOI=10.1002/(SICI)1097-0215(19970807)72:4<700::AID-IJC24>3.0.CO;2-D;
RA   Dorssers, Lambert C.J.
RA   Veldscholte, Jos Willibrordus
RT   "Identification of a novel breast-cancer-anti-estrogen-resistance
RT   (BCAR2) locus by cell-fusion-mediated gene transfer in human
RT   breast-cancer cells.";
RL   Int. J. Cancer 72:700-705(1997).
//