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Cellosaurus L1210/6MP (CVCL_E2YE)

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Cell line name L1210/6MP
Synonyms L1210/MP; L1210/6-MP (NSC-755)
Accession CVCL_E2YE
Resource Identification Initiative To cite this cell line use: L1210/6MP (RRID:CVCL_E2YE)
Comments Selected for resistance to: ChEBI; CHEBI_50667; Mercaptopurine (6-MP).
Transformant: ChEBI; CHEBI_34342; 3-methylcholanthrene (3-MC; 20-methylcholanthrene; 20-MC; MCA).
Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
Cell type: T-cell; CL=CL_0000084.
Disease Mouse leukemia (NCIt: C21604)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: DBA/2.
Hierarchy Parent: CVCL_0382 (L1210)
Sex of cell Female
Age at sampling 8M
Category Cancer cell line
Publications

PubMed=13804596
Robert Wallace Brockman;
A mechanism of resistance to 6-mercaptopurine: metabolism of hypoxanthine and 6-mercaptopurine by sensitive and resistant neoplasms.
Cancer Res. 20:643-653(1960)

PubMed=6890814; DOI=10.1016/0006-2952(82)90096-x
Janna Diane Strobel-Stevens, Salah M. El Dareer, Mary W. Trader, Donald L. Hill;
Some biochemical characteristics of L1210 cell lines resistant to 6-mercaptopurine and 6-thioguanine and with increased sensitivity to methotrexate.
Biochem. Pharmacol. 31:3133-3137(1982)

Cross-references
Cell line collections (Providers) NCI-DCTD; L1210/6-MP (NSC-755)
Entry history
Entry creation10-Sep-2024
Last entry update25-Jun-2026
Version number3