ID   L1210/6MP
AC   CVCL_E2YE
SY   L1210/MP
RX   PubMed=6890814;
RX   PubMed=13804596;
CC   Selected for resistance to: ChEBI; CHEBI_50667; Mercaptopurine (6-MP).
CC   Transformant: ChEBI; CHEBI_34342; 3-methylcholanthrene (3-MC; 20-methylcholanthrene; 20-MC; MCA).
CC   Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
CC   Cell type: T-cell; CL=CL_0000084.
CC   Breed/subspecies: DBA/2.
DI   NCIt; C21604; Mouse leukemia
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_0382 ! L1210
SX   Female
AG   8M
CA   Cancer cell line
DT   Created: 10-09-24; Last updated: 19-12-24; Version: 2
//
RX   PubMed=6890814; DOI=10.1016/0006-2952(82)90096-x;
RA   Strobel-Stevens J.D., El Dareer S.M., Trader M.W., Hill D.L.;
RT   "Some biochemical characteristics of L1210 cell lines resistant to
RT   6-mercaptopurine and 6-thioguanine and with increased sensitivity to
RT   methotrexate.";
RL   Biochem. Pharmacol. 31:3133-3137(1982).
//
RX   PubMed=13804596;
RA   Brockman R.W.;
RT   "A mechanism of resistance to 6-mercaptopurine: metabolism of
RT   hypoxanthine and 6-mercaptopurine by sensitive and resistant
RT   neoplasms.";
RL   Cancer Res. 20:643-653(1960).
//