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Cellosaurus MKN45/CV (CVCL_E2W7)

[Text version]
Cell line name MKN45/CV
Synonyms MKN-45/CV
Accession CVCL_E2W7
Resource Identification Initiative To cite this cell line use: MKN45/CV (RRID:CVCL_E2W7)
Comments Population: Japanese.
Characteristics: Control cell line for MKN45/TP (Cellosaurus=CVCL_9645) (PubMed=18922971).
Doubling time: 38 hours (PubMed=18922971).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Derived from site: Metastatic; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg110Cys (c.328C>T); ClinVar=VCV000142206; Zygosity=Heterozygous (from parent cell line).
Disease Gastric adenocarcinoma (NCIt: C4004)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0434 (MKN45)
Sex of cell Female
Age at sampling 62Y
Category Cancer cell line
Publications

PubMed=18922971; DOI=10.1158/1541-7786.MCR-08-0166
Eun Jeong Yu, Young Lee, Sun Young Rha, Tae Soo Kim, Hyun Cheol Chung, Bong Kyeong Oh, Woo Ick Yang, Sung Hoon Noh, Hei-Cheul Jeung;
Angiogenic factor thymidine phosphorylase increases cancer cell invasion activity in patients with gastric adenocarcinoma.
Mol. Cancer Res. 6:1554-1566(2008)

Entry history
Entry creation10-Sep-2024
Last entry update14-Aug-2025
Version number3