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Cellosaurus MKN45/TP (CVCL_9645)

[Text version]
Cell line name MKN45/TP
Synonyms MKN-45/TP
Accession CVCL_9645
Resource Identification Initiative To cite this cell line use: MKN45/TP (RRID:CVCL_9645)
Comments Population: Japanese.
Doubling time: 33 hours (PubMed=18922971).
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:3148; TYMP.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Derived from site: Metastatic; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg110Cys (c.328C>T); ClinVar=VCV000142206; Zygosity=Heterozygous (from parent cell line).
Disease Gastric adenocarcinoma (NCIt: C4004)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0434 (MKN45)
Sex of cell Female
Age at sampling 62Y
Category Cancer cell line
Publications

PubMed=18922971; DOI=10.1158/1541-7786.MCR-08-0166
Eun Jeong Yu, Young Lee, Sun Young Rha, Tae Soo Kim, Hyun Cheol Chung, Bong Kyeong Oh, Woo Ick Yang, Sung Hoon Noh, Hei-Cheul Jeung;
Angiogenic factor thymidine phosphorylase increases cancer cell invasion activity in patients with gastric adenocarcinoma.
Mol. Cancer Res. 6:1554-1566(2008)

Cross-references
Cell line databases/resources cancercelllines; CVCL_9645
Encyclopedic resources Wikidata; Q54905826
Entry history
Entry creation06-Jun-2012
Last entry update14-Aug-2025
Version number20