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Cellosaurus MDAH041 (CVCL_E212)

[Text version]
Cell line name MDAH041
Synonyms MDAH 041; 041S
Accession CVCL_E212
Resource Identification Initiative To cite this cell line use: MDAH041 (RRID:CVCL_E212)
Disease Li-Fraumeni syndrome (NCIt: C3476)
Li-Fraumeni syndrome (ORDO: Orphanet_524)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_IM77 (TR9-7)
Sex of cell Female
Age at sampling 22Y
Category Cancer cell line

Little J.B., Nove J., Dahlberg W.K., Troilo P., Nichols W.W., Strong L.C.
Normal cytotoxic response of skin fibroblasts from patients with Li-Fraumeni familial cancer syndrome to DNA-damaging agents in vitro.
Cancer Res. 47:4229-4234(1987)

Bischoff F.Z., Yim S.O., Pathak S., Grant G., Siciliano M.J., Giovanella B.C., Strong L.C., Tainsky M.A.
Spontaneous abnormalities in normal fibroblasts from patients with Li-Fraumeni cancer syndrome: aneuploidy and immortalization.
Cancer Res. 50:7979-7984(1990)

Bischoff F.Z., Strong L.C., Yim S.O., Pratt D.R., Siciliano M.J., Giovanella B.C., Tainsky M.A.
Tumorigenic transformation of spontaneously immortalized fibroblasts from patients with a familial cancer syndrome.
Oncogene 6:183-186(1991)

PubMed=7667317; DOI=10.1073/pnas.92.18.8493
Agarwal M.L., Agarwal A., Taylor W.R., Stark G.R.
p53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts.
Proc. Natl. Acad. Sci. U.S.A. 92:8493-8497(1995)

Encyclopedic resources Wikidata; Q54904670
Entry history
Entry creation22-Oct-2012
Last entry update21-Mar-2023
Version number9