Cellosaurus logo
expasy logo

Cellosaurus TR9-7 (CVCL_IM77)

[Text][XML][JSON]
Cell line name TR9-7
Synonyms Tr9-7
Accession CVCL_IM77
Resource Identification Initiative To cite this cell line use: TR9-7 (RRID:CVCL_IM77)
Comments Characteristics: Expresses wild-type TP53 under the control of a tetracycline-regulated promoter.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:11998; TP53.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Omics: Transcriptomics; Microarray.
Disease Li-Fraumeni syndrome (NCIt: C3476)
Li-Fraumeni syndrome (ORDO: Orphanet_524)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_E212 (MDAH041)
Sex of cell Female
Age at sampling 22Y
Category Cancer cell line
Publications

PubMed=7667317; DOI=10.1073/pnas.92.18.8493; PMCID=PMC41183
Munna L. Agarwal, Archana Agarwal, William R. Taylor, George Robert Stark;
p53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts.
Proc. Natl. Acad. Sci. U.S.A. 92:8493-8497(1995)

PubMed=16966095; DOI=10.1289/ehp.8969; PMCID=PMC1570045
Samuel C. McNeely, Xiao-Giang Xu, B. Frazier Taylor, Wolfgang Zacharias, Michael J. McCabe Jr., J. Christopher States;
Exit from arsenite-induced mitotic arrest is p53 dependent.
Environ. Health Perspect. 114:1401-1406(2006)

Cross-references
Encyclopedic resources Wikidata; Q54972936
Gene expression databases GEO; GSE7101
Entry history
Entry creation01-Dec-2016
Last entry update14-Aug-2025
Version number11