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Cellosaurus NGC-0295 (CVCL_DF66)

[Text version]
Cell line name NGC-0295
Synonyms NGC0295
Accession CVCL_DF66
Resource Identification Initiative To cite this cell line use: NGC-0295 (RRID:CVCL_DF66)
Comments Biotechnology: Used in NsG0202, an encapsulated cell biodelivery device capable of local delivery of NGF to the brain so at to treat the cognitive decline in Alzheimer disease patients.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:7808; NGF.
Derived from site: In situ; Eye, retina, retinal pigment epithelium; UBERON=UBERON_0001782.
Cell type: Retinal pigment epithelial cell; CL=CL_0002586.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0145 (ARPE-19)
Sex of cell Male
Age at sampling 19Y
Category Spontaneously immortalized cell line
Publications

PubMed=20664524; DOI=10.1038/mt.2010.154; PMCID=PMC2997581
Lone Fjord-Larsen, Philip Kusk, Jens Tornoe, Bengt Juliusson, Malene Torp, Carsten Reidies Bjarkam, Mette S. Nielsen, Aase Handberg, Jens Christian Hedemann Sorensen, Lars U. Wahlberg;
Long-term delivery of nerve growth factor by encapsulated cell biodelivery in the Gottingen minipig basal forebrain.
Mol. Ther. 18:2164-2172(2010)

PubMed=22113314; DOI=10.1038/gt.2011.178
Lone Fjord-Larsen, Philip Kusk, Dwaine F. Emerich, Christopher G. Thanos, Malene Torp, Briannan Bintz, Jens Tornoe, Anders H. Johnsen, Lars U. Wahlberg;
Increased encapsulated cell biodelivery of nerve growth factor in the brain by transposon-mediated gene transfer.
Gene Ther. 19:1010-1017(2012)

PubMed=22655593; DOI=10.3171/2012.2.JNS11714
Lars U. Wahlberg, Goran Lind, Per M. Almqvist, Philip Kusk, Jens Tornoe, Bengt Juliusson, Michael Soderman, Eva Sellden, Ake Seiger, Maria Eriksdotter-Jonhagen, Bengt Linderoth;
Targeted delivery of nerve growth factor via encapsulated cell biodelivery in Alzheimer disease: a technology platform for restorative neurosurgery.
J. Neurosurg. 117:340-347(2012)

Cross-references
Encyclopedic resources Wikidata; Q54930462
Entry history
Entry creation13-Jul-2016
Last entry update19-Dec-2024
Version number11