Cellosaurus cell line NGC-0295 (CVCL

Cellosaurus NGC-0295 (CVCL_DF66)

Cross-references
Cell line name	NGC-0295
Synonyms	NGC0295
Accession	CVCL_DF66
Resource Identification Initiative	To cite this cell line use: NGC-0295 (RRID:CVCL_DF66)
Comments	Biotechnology: Used in NsG0202, an encapsulated cell biodelivery device capable of local delivery of NGF to the brain so at to treat the cognitive decline in Alzheimer disease patients. Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:7808; NGF. Derived from site: In situ; Eye, retina, retinal pigment epithelium; UBERON=UBERON_0001782. Cell type: Retinal pigment epithelial cell; CL=CL_0002586.
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0145 (ARPE-19)
Sex of cell	Male
Age at sampling	19Y
Category	Spontaneously immortalized cell line
Publications	PubMed=20664524; DOI=10.1038/mt.2010.154; PMCID=PMC2997581 Lone Fjord-Larsen, Philip Kusk, Jens Tornoe, Bengt Juliusson, Malene Torp, Carsten Reidies Bjarkam, Mette S. Nielsen, Aase Handberg, Jens Christian Hedemann Sorensen, Lars U. Wahlberg; Long-term delivery of nerve growth factor by encapsulated cell biodelivery in the Gottingen minipig basal forebrain. Mol. Ther. 18:2164-2172(2010) PubMed=22113314; DOI=10.1038/gt.2011.178 Lone Fjord-Larsen, Philip Kusk, Dwaine F. Emerich, Christopher G. Thanos, Malene Torp, Briannan Bintz, Jens Tornoe, Anders H. Johnsen, Lars U. Wahlberg; Increased encapsulated cell biodelivery of nerve growth factor in the brain by transposon-mediated gene transfer. Gene Ther. 19:1010-1017(2012) PubMed=22655593; DOI=10.3171/2012.2.JNS11714 Lars U. Wahlberg, Goran Lind, Per M. Almqvist, Philip Kusk, Jens Tornoe, Bengt Juliusson, Michael Soderman, Eva Sellden, Ake Seiger, Maria Eriksdotter-Jonhagen, Bengt Linderoth; Targeted delivery of nerve growth factor via encapsulated cell biodelivery in Alzheimer disease: a technology platform for restorative neurosurgery. J. Neurosurg. 117:340-347(2012)
Encyclopedic resources	Wikidata; Q54930462
Entry history
Entry creation	13-Jul-2016
Last entry update	19-Dec-2024
Version number	11