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Cellosaurus NGC0211 (CVCL_DF65)

[Text version]
Cell line name NGC0211
Accession CVCL_DF65
Resource Identification Initiative To cite this cell line use: NGC0211 (RRID:CVCL_DF65)
Comments Biotechnology: Used in NsG0202.1, an encapsulated cell biodelivery device capable of local delivery of NGF to the brain so at to treat the cognitive decline in Alzheimer disease patients.
Characteristics: Contains 4 integrated copies of the NGF gene.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:7808; NGF.
Derived from site: In situ; Eye, retina, retinal pigment epithelium; UBERON=UBERON_0001782.
Cell type: Retinal pigment epithelial cell; CL=CL_0002586.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0145 (ARPE-19)
Sex of cell Male
Age at sampling 19Y
Category Spontaneously immortalized cell line
Publications

DOI=10.2174/1875043501205010035
Lone Fjord-Larsen, Philip Kusk, Malene Torp, Jens Christian Hedemann Sorensen, Kaare Ettrup, Carsten Reidies Bjarkam, Jens Tornoe, Bengt Juliusson, Lars U. Wahlberg;
Encapsulated cell biodelivery of transposon-mediated high-dose NGF to the Gottingen mini pig basal forebrain.
Open Tissue Eng. Regen. Med. J. 5:35-42(2012)

PubMed=22113314; DOI=10.1038/gt.2011.178
Lone Fjord-Larsen, Philip Kusk, Dwaine F. Emerich, Christopher G. Thanos, Malene Torp, Briannan Bintz, Jens Tornoe, Anders H. Johnsen, Lars U. Wahlberg;
Increased encapsulated cell biodelivery of nerve growth factor in the brain by transposon-mediated gene transfer.
Gene Ther. 19:1010-1017(2012)

Cross-references
Encyclopedic resources Wikidata; Q54930466
Entry history
Entry creation13-Jul-2016
Last entry update19-Dec-2024
Version number11