ID   NGC0211
AC   CVCL_DF65
DR   Wikidata; Q54930466
RX   DOI=10.2174/1875043501205010035;
RX   PubMed=22113314;
CC   Biotechnology: Used in NsG0202.1, an encapsulated cell biodelivery device capable of local delivery of NGF to the brain so at to treat the cognitive decline in Alzheimer disease patients.
CC   Characteristics: Contains 4 integrated copies of the NGF gene.
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:7808; NGF.
CC   Derived from site: In situ; Eye, retina, retinal pigment epithelium; UBERON=UBERON_0001782.
CC   Cell type: Retinal pigment epithelial cell; CL=CL_0002586.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0145 ! ARPE-19
SX   Male
AG   19Y
CA   Spontaneously immortalized cell line
DT   Created: 13-07-16; Last updated: 19-12-24; Version: 11
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RX   DOI=10.2174/1875043501205010035;
RA   Fjord-Larsen L., Kusk P., Torp M., Sorensen J.C.H., Ettrup K.,
RA   Bjarkam C.R., Tornoe J., Juliusson B., Wahlberg L.U.;
RT   "Encapsulated cell biodelivery of transposon-mediated high-dose NGF to
RT   the Gottingen mini pig basal forebrain.";
RL   Open Tissue Eng. Regen. Med. J. 5:35-42(2012).
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RX   PubMed=22113314; DOI=10.1038/gt.2011.178;
RA   Fjord-Larsen L., Kusk P., Emerich D.F., Thanos C.G., Torp M., Bintz B.,
RA   Tornoe J., Johnsen A.H., Wahlberg L.U.;
RT   "Increased encapsulated cell biodelivery of nerve growth factor in the
RT   brain by transposon-mediated gene transfer.";
RL   Gene Ther. 19:1010-1017(2012).
//