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Cellosaurus PK-9 [Human] (CVCL_D721)

[Text version]
Cell line name PK-9 [Human]
Synonyms PK 9; Pk 9; PK9
Accession CVCL_D721
Resource Identification Initiative To cite this cell line use: PK-9 [Human] (RRID:CVCL_D721)
Comments Population: Japanese.
Doubling time: 72 hours (PubMed=3547771; PubMed=7622937); 51.4 hours (PubMed=8872523).
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; miRNA profiling; Microarray.
Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Sequence variations
Disease Pancreatic ductal adenocarcinoma (NCIt: C9120)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_0B33 (RPK-9)
Sex of cell Male
Age at sampling 53Y
Category Cancer cell line
STR profile Source(s): TKG=TKG 0240

Markers:
AmelogeninX,Y
CSF1PO12
D5S81811,12
D7S82011
D13S3179,10
D16S53912
TH019
TPOX9,11
vWA15,19

Run an STR similarity search on this cell line
Publications

PubMed=3547771; DOI=10.1620/tjem.150.231
Masao Kobari, Hirotake Hisano, Seiki Matsuno, Toshio Sato, Mikio Kan, Takehiko Tachibana;
Establishment of six human pancreatic cancer cell lines and their sensitivities to anti-tumor drugs.
Tohoku J. Exp. Med. 150:231-248(1986)

PubMed=7622937; DOI=10.1007/BF02788531
Katsumi Amikura, Masao Kobari, Seiki Matsuno;
The time of occurrence of liver metastasis in carcinoma of the pancreas.
Int. J. Pancreatol. 17:139-146(1995)

PubMed=8872523; DOI=10.1007/BF02787375
Yoshiaru Kimura, Masao Kobari, Tohru Yusa, Makoto Sunamura, M. Kimura, Hiromune Shimamura, Seiki Matsuno;
Establishment of an experimental liver metastasis model by intraportal injection of a newly derived human pancreatic cancer cell line (KLM-1).
Int. J. Pancreatol. 20:43-50(1996)

PubMed=11115575; DOI=10.3892/or.8.1.89
Chun-Lan Sun, Takashi Yamato, Toru Furukawa, Yasuyuki Ohnishi, Hiroshi Kijima, Akira Horii;
Characterization of the mutations of the K-ras, p53, p16, and SMAD4 genes in 15 human pancreatic cancer cell lines.
Oncol. Rep. 8:89-92(2001)

PubMed=15770730; DOI=10.3748/wjg.v11.i10.1521; PMCID=PMC4305696
Jian-Hua Ma, Emilia Patrut, Jan Schmidt, Hanns-Peter Knaebel, Markus Wolfgang Buchler, Alexandra Marten;
Synergistic effects of interferon-alpha in combination with chemoradiation on human pancreatic adenocarcinoma.
World J. Gastroenterol. 11:1521-1528(2005)

PubMed=16912165; DOI=10.1158/0008-5472.CAN-06-0721
Eric S. Calhoun, Tomas Hucl, Eike Gallmeier, Kristen M. West, Dan E. Arking, Anirban Maitra, Christine A. Iacobuzio-Donahue, Aravinda Chakravarti, Ralph H. Hruban, Scott E. Kern;
Identifying allelic loss and homozygous deletions in pancreatic cancer without matched normals using high-density single-nucleotide polymorphism arrays.
Cancer Res. 66:7920-7928(2006)

DOI=10.22029/jlupub-12385
Laura Oberlin;
Treatment of pancreatic carcinoma cell lines in vitro and vivo with a monoclonal antibody against the transferrin receptor.
Thesis VMD (2009); Justus-Liebig-Universitat Giessen; Giessen; Germany

PubMed=20037478; DOI=10.4161/cbt.8.21.9685; PMCID=PMC2824894
Oliver A. Kent, Michael E. Mullendore, Eric A. Wentzel, Pedro Lopez-Romero, Aik-Choon Tan, Hector Alvarez, Kristen M. West, Michael F. Ochs, Manuel Hidalgo, Dan E. Arking, Anirban Maitra, Joshua T. Mendell;
A resource for analysis of microRNA expression and function in pancreatic ductal adenocarcinoma cells.
Cancer Biol. Ther. 8:2013-2024(2009)

PubMed=22490663; DOI=10.1016/j.bbrc.2012.03.122
Yuriko Saiki, Yuki Yoshino, Hiroko Fujimura, Tatsuya Manabe, Yuki Kudo, Miki Shimada, Nariyasu Mano, Tomohiro Nakano, Yoonha Lee, Shinjiro Shimizu, Shinya Oba ...Show all 23 authors... , Sho Fujiwara, Hideyuki Shimizu, Na Chen, Zhaleh Kashkouli Nezhad, Guo Jin, Shinichi Fukushige, Makoto Sunamura, Masaharu Ishida, Fuyuhiko Motoi, Shinichi Egawa, Michiaki Unno, Akira Horii; Show fewer authors
DCK is frequently inactivated in acquired gemcitabine-resistant human cancer cells.
Biochem. Biophys. Res. Commun. 421:98-104(2012)

Cross-references
Cell line collections (Providers) RCB; RCB2140 - Discontinued
TKG; TKG 0240
Cell line databases/resources cancercelllines; CVCL_D721
Anatomy/cell type resources BTO; BTO_0005486
Chemistry resources ChEMBL-Cells; CHEMBL4295487
ChEMBL-Targets; CHEMBL4296486
PubChem_Cell_line; CVCL_D721
Encyclopedic resources Wikidata; Q54947461
Gene expression databases GEO; GSM862568
GEO; GSM862570
GEO; GSM1588618
GEO; GSM1588630
Polymorphism and mutation databases Cosmic; 707255
Cosmic; 1066178
Cosmic; 1644299
IARC_TP53; 14303
Entry history
Entry creation22-Oct-2012
Last entry update10-Apr-2025
Version number26