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Cellosaurus PK-9 [Human] (CVCL_D721)

[Text version]
Cell line name PK-9 [Human]
Synonyms PK 9; Pk 9; PK9
Accession CVCL_D721
Resource Identification Initiative To cite this cell line use: PK-9 [Human] (RRID:CVCL_D721)
Comments Population: Japanese.
Doubling time: 72 hours (PubMed=3547771; PubMed=7622937); 51.4 hours (PubMed=8872523).
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Sequence variations
Disease Pancreatic ductal adenocarcinoma (NCIt: C9120)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_0B33 (RPK-9)
Sex of cell Male
Age at sampling 53Y
Category Cancer cell line
STR profile Source(s): TKG=TKG 0240

Markers:
AmelogeninX,Y
CSF1PO12
D5S81811,12
D7S82011
D13S3179,10
D16S53912
TH019
TPOX9,11
vWA15,19

Run an STR similarity search on this cell line
Publications

PubMed=3547771; DOI=10.1620/tjem.150.231
Kobari M., Hisano H., Matsuno S., Sato T., Kan M., Tachibana T.
Establishment of six human pancreatic cancer cell lines and their sensitivities to anti-tumor drugs.
Tohoku J. Exp. Med. 150:231-248(1986)

PubMed=7622937; DOI=10.1007/BF02788531
Amikura K., Kobari M., Matsuno S.
The time of occurrence of liver metastasis in carcinoma of the pancreas.
Int. J. Pancreatol. 17:139-146(1995)

PubMed=8872523; DOI=10.1007/BF02787375
Kimura Y., Kobari M., Yusa T., Sunamura M., Kimura M., Shimamura H., Matsuno S.
Establishment of an experimental liver metastasis model by intraportal injection of a newly derived human pancreatic cancer cell line (KLM-1).
Int. J. Pancreatol. 20:43-50(1996)

PubMed=11115575; DOI=10.3892/or.8.1.89
Sun C.-L., Yamato T., Furukawa T., Ohnishi Y., Kijima H., Horii A.
Characterization of the mutations of the K-ras, p53, p16, and SMAD4 genes in 15 human pancreatic cancer cell lines.
Oncol. Rep. 8:89-92(2001)

PubMed=15770730; DOI=10.3748/wjg.v11.i10.1521
Ma J.-H., Patrut E., Schmidt J., Knaebel H.-P., Buchler M.W., Marten A.
Synergistic effects of interferon-alpha in combination with chemoradiation on human pancreatic adenocarcinoma.
World J. Gastroenterol. 11:1521-1528(2005)

PubMed=16912165; DOI=10.1158/0008-5472.CAN-06-0721
Calhoun E.S., Hucl T., Gallmeier E., West K.M., Arking D.E., Maitra A., Iacobuzio-Donahue C.A., Chakravarti A., Hruban R.H., Kern S.E.
Identifying allelic loss and homozygous deletions in pancreatic cancer without matched normals using high-density single-nucleotide polymorphism arrays.
Cancer Res. 66:7920-7928(2006)

CLPUB00416
Oberlin L.
Treatment of pancreatic carcinoma cell lines in vitro and vivo with a monoclonal antibody against the transferrin receptor.
Thesis VMD (2009), Justus-Liebig-Universitat Giessen, Germany

PubMed=22490663; DOI=10.1016/j.bbrc.2012.03.122
Saiki Y., Yoshino Y., Fujimura H., Manabe T., Kudo Y., Shimada M., Mano N., Nakano T., Lee Y., Shimizu S., Oba S., Fujiwara S., Shimizu H., Chen N., Nezhad Z.K., Jin G., Fukushige S., Sunamura M., Ishida M., Motoi F., Egawa S., Unno M., Horii A.
DCK is frequently inactivated in acquired gemcitabine-resistant human cancer cells.
Biochem. Biophys. Res. Commun. 421:98-104(2012)

Cross-references
Cell line collections (Providers) RCB; RCB2140 - Discontinued
TKG; TKG 0240
Cell line databases/resources cancercelllines; CVCL_D721
Anatomy/cell type resources BTO; BTO:0005486
Chemistry resources ChEMBL-Cells; CHEMBL4295487
ChEMBL-Targets; CHEMBL4296486
PubChem_Cell_line; CVCL_D721
Encyclopedic resources Wikidata; Q54947461
Gene expression databases GEO; GSM862568
GEO; GSM862570
GEO; GSM1588618
GEO; GSM1588630
Polymorphism and mutation databases Cosmic; 707255
Cosmic; 1066178
Cosmic; 1644299
IARC_TP53; 14303
Entry history
Entry creation22-Oct-2012
Last entry update02-May-2024
Version number23