Cellosaurus cell line RPK-9 (CVCL

Cellosaurus RPK-9 (CVCL_0B33)

Cross-references
Cell line name	RPK-9
Synonyms	RPK9
Accession	CVCL_0B33
Resource Identification Initiative	To cite this cell line use: RPK-9 (RRID:CVCL_0B33)
Comments	Population: Japanese. Selected for resistance to: ChEBI; CHEBI:175901; Gemcitabine (Gemzar). Omics: Transcriptome analysis by microarray. Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Sequence variations	Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Unspecified (PubMed=22490663). Mutation; HGNC; 11998; TP53; Simple; p.Arg213Ter (c.637C>T); ClinVar=VCV000043590; Zygosity=Unspecified (PubMed=22490663).
Disease	Pancreatic ductal adenocarcinoma (NCIt: C9120)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_D721 (PK-9 [Human])
Sex of cell	Male
Age at sampling	53Y
Category	Cancer cell line
Publications	PubMed=22490663; DOI=10.1016/j.bbrc.2012.03.122 Saiki Y., Yoshino Y., Fujimura H., Manabe T., Kudo Y., Shimada M., Mano N., Nakano T., Lee Y., Shimizu S., Oba S., Fujiwara S., Shimizu H., Chen N., Nezhad Z.K., Jin G., Fukushige S., Sunamura M., Ishida M., Motoi F., Egawa S., Unno M., Horii A. DCK is frequently inactivated in acquired gemcitabine-resistant human cancer cells. Biochem. Biophys. Res. Commun. 421:98-104(2012)
Cell line databases/resources	cancercelllines; CVCL_0B33
Anatomy/cell type resources	BTO; BTO:0005469
Encyclopedic resources	Wikidata; Q54951156
Gene expression databases	GEO; GSM862569 GEO; GSM862571
Entry history
Entry creation	10-Apr-2015
Last entry update	05-Oct-2023
Version number	12