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Cellosaurus HBEC3-ET (CVCL_D4C2)

[Text version]
Cell line name HBEC3-ET
Synonyms HBEC3 HPV16 E6/E7 hTERT
Accession CVCL_D4C2
Resource Identification Initiative To cite this cell line use: HBEC3-ET (RRID:CVCL_D4C2)
Comments Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=MGI; MGI:88357; Cdk4.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Lung, bronchus, epithelium; UBERON=UBERON_0002031.
Cell type: Epithelial cell of bronchus; CL=CL_0002328.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_X491 ! HBEC3-KT
Sex of cell Female
Age at sampling 65Y
Category Transformed cell line
Publications

PubMed=15604268; DOI=10.1158/0008-5472.CAN-04-3703
Ramirez R.D., Sheridan S., Girard L., Sato M., Kim Y., Pollack J., Peyton M., Zou Y., Kurie J.M., DiMaio J.M., Milchgrub S., Smith A.L., Souza R.F., Gilbey L., Zhang X., Gandia K.G., Vaughan M.B., Wright W.E., Gazdar A.F., Shay J.W., Minna J.D.
Immortalization of human bronchial epithelial cells in the absence of viral oncoproteins.
Cancer Res. 64:9027-9034(2004)

Cross-references
Encyclopedic resources Wikidata; Q127381112
Gene expression databases GEO; GSM171894
Entry history
Entry creation30-Jan-2024
Last entry update10-Apr-2025
Version number4