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Cellosaurus HBEC3-ET (CVCL_D4C2)

[Text version]
Cell line name HBEC3-ET
Synonyms HBEC3 HPV16 E6/E7 hTERT
Accession CVCL_D4C2
Resource Identification Initiative To cite this cell line use: HBEC3-ET (RRID:CVCL_D4C2)
Comments Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=MGI; MGI:88357; Cdk4.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Lung, bronchus, epithelium; UBERON=UBERON_0002031.
Cell type: Epithelial cell of bronchus; CL=CL_0002328.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_X491 ! HBEC3-KT
Sex of cell Female
Age at sampling 65Y
Category Transformed cell line
Publications

PubMed=15604268; DOI=10.1158/0008-5472.CAN-04-3703
Ruben D. Ramirez, Shelley Sheridan, Luc Girard, Mitsuo Sato, Young Kim, Jon Pollack, Michael Peyton, Ying Zou, Jonathan M. Kurie, J. Michael DiMaio, Sara Milchgrub ...Show all 21 authors... , Alice L. Smith, Rhonda F. Souza, Laura Gilbey, Xi Zhang, Kenia G. Gandia, Melville B. Vaughan, Woodring Erik Wright, Adi F. Gazdar, Jerry W. Shay, John D. Minna; Show fewer authors
Immortalization of human bronchial epithelial cells in the absence of viral oncoproteins.
Cancer Res. 64:9027-9034(2004)

Cross-references
Encyclopedic resources Wikidata; Q127381112
Gene expression databases GEO; GSM171894
Entry history
Entry creation30-Jan-2024
Last entry update14-Aug-2025
Version number5