Cellosaurus cell line HBEC3-ET (CVCL

Cellosaurus HBEC3-ET (CVCL_D4C2)

Cross-references
Cell line name	HBEC3-ET
Synonyms	HBEC3 HPV16 E6/E7 hTERT
Accession	CVCL_D4C2
Resource Identification Initiative	To cite this cell line use: HBEC3-ET (RRID:CVCL_D4C2)
Comments	Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT. Genetic integration: Method=Transduction; Gene=MGI; MGI:88357; Cdk4. Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo. Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR). Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16). Omics: Transcriptomics; Microarray. Derived from site: In situ; Lung, bronchus, epithelium; UBERON=UBERON_0002031. Cell type: Epithelial cell of bronchus; CL=CL_0002328.
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual	CVCL_X491 ! HBEC3-KT
Sex of cell	Female
Age at sampling	65Y
Category	Transformed cell line
Publications	PubMed=15604268; DOI=10.1158/0008-5472.CAN-04-3703 Ruben D. Ramirez, Shelley Sheridan, Luc Girard, Mitsuo Sato, Young Kim, Jon Pollack, Michael Peyton, Ying Zou, Jonathan M. Kurie, J. Michael DiMaio, Sara Milchgrub ...Show all 21 authors... , Alice L. Smith, Rhonda F. Souza, Laura Gilbey, Xi Zhang, Kenia G. Gandia, Melville B. Vaughan, Woodring Erik Wright, Adi F. Gazdar, Jerry W. Shay, John D. Minna; Show fewer authors Immortalization of human bronchial epithelial cells in the absence of viral oncoproteins. Cancer Res. 64:9027-9034(2004)
Encyclopedic resources	Wikidata; Q127381112
Gene expression databases	GEO; GSM171894
Entry history
Entry creation	30-Jan-2024
Last entry update	14-Aug-2025
Version number	5