ID   HBEC3-ET
AC   CVCL_D4C2
SY   HBEC3 HPV16 E6/E7 hTERT
DR   GEO; GSM171894
DR   Wikidata; Q127381112
RX   PubMed=15604268;
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
CC   Genetic integration: Method=Transduction; Gene=MGI; MGI:88357; Cdk4.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
CC   Omics: Transcriptomics; Microarray.
CC   Derived from site: In situ; Lung, bronchus, epithelium; UBERON=UBERON_0002031.
CC   Cell type: Epithelial cell of bronchus; CL=CL_0002328.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_X491 ! HBEC3-KT
SX   Female
AG   65Y
CA   Transformed cell line
DT   Created: 30-01-24; Last updated: 10-04-25; Version: 4
//
RX   PubMed=15604268; DOI=10.1158/0008-5472.CAN-04-3703;
RA   Ramirez R.D., Sheridan S., Girard L., Sato M., Kim Y., Pollack J.,
RA   Peyton M., Zou Y., Kurie J.M., DiMaio J.M., Milchgrub S., Smith A.L.,
RA   Souza R.F., Gilbey L., Zhang X., Gandia K.G., Vaughan M.B., Wright W.E.,
RA   Gazdar A.F., Shay J.W., Minna J.D.;
RT   "Immortalization of human bronchial epithelial cells in the absence of
RT   viral oncoproteins.";
RL   Cancer Res. 64:9027-9034(2004).
//