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Cellosaurus CCArly CAF (CVCL_D4A6)

[Text version]
Cell line name CCArly CAF
Accession CVCL_D4A6
Resource Identification Initiative To cite this cell line use: CCArly CAF (RRID:CVCL_D4A6)
Comments Population: Caucasian.
Characteristics: This is a TERT-immortalized cancer-associated fibroblast cell line which is used for the growth of a 3D co-culture tumor model (CCTM) that requires co-culture of this cell line with cancer cell line MUG-CCArly (Cellosaurus=CVCL_D4A5) (PubMed=36980644).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Derived from site: In situ; Extrahepatic bile duct; UBERON=UBERON_0003703.
Cell type: Fibroblast; CL=CL_0000057.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_D4A5 ! MUG-CCArly
Sex of cell Female
Age at sampling 72Y
Category Telomerase immortalized cell line
Publications

PubMed=36980644; DOI=10.3390/cancers15061757; PMCID=PMC10046314
Silke Schrom, Florian Kleinegger, Ines Anders, Thomas Hebesberger, Christina Karner, Laura Liesinger, Ruth Birner-Gruenberger, Wilfried Renner, Martin Pichler, Regina Grillari-Voglauer, Ariane Aigelsreiter, Beate Rinner;
MUG CCArly: a novel autologous 3D cholangiocarcinoma model presents an increased angiogenic potential.
Cancers (Basel) 15:1757.1-1757.21(2023)

Cross-references
Encyclopedic resources Wikidata; Q127380419
Entry history
Entry creation30-Jan-2024
Last entry update19-Dec-2024
Version number3