ID   CCArly CAF
AC   CVCL_D4A6
DR   Wikidata; Q127380419
RX   PubMed=36980644;
CC   Population: Caucasian.
CC   Characteristics: This is a TERT-immortalized cancer-associated fibroblast cell line which is used for the growth of a 3D co-culture tumor model (CCTM) that requires co-culture of this cell line with cancer cell line MUG-CCArly (Cellosaurus=CVCL_D4A5) (PubMed=36980644).
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
CC   Derived from site: In situ; Extrahepatic bile duct; UBERON=UBERON_0003703.
CC   Cell type: Fibroblast; CL=CL_0000057.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_D4A5 ! MUG-CCArly
SX   Female
AG   72Y
CA   Telomerase immortalized cell line
DT   Created: 30-01-24; Last updated: 19-12-24; Version: 3
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RX   PubMed=36980644; DOI=10.3390/cancers15061757; PMCID=PMC10046314;
RA   Schrom S., Kleinegger F., Anders I., Hebesberger T., Karner C.,
RA   Liesinger L., Birner-Gruenberger R., Renner W., Pichler M.,
RA   Grillari-Voglauer R., Aigelsreiter A., Rinner B.;
RT   "MUG CCArly: a novel autologous 3D cholangiocarcinoma model presents
RT   an increased angiogenic potential.";
RL   Cancers (Basel) 15:1757.1-1757.21(2023).
//