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Cellosaurus MUG-CCArly (CVCL_D4A5)

[Text version]
Cell line name MUG-CCArly
Synonyms MUG CCArly
Accession CVCL_D4A5
Resource Identification Initiative To cite this cell line use: MUG-CCArly (RRID:CVCL_D4A5)
Comments Population: Caucasian.
Characteristics: Grows as 3D co-culture tumor model (CCTM) that requires co-culture of this cell line with the cancer-associated fibroblast cell line CCArly CAF (Cellosaurus=CVCL_D4A6) (PubMed=36980644).
Doubling time: ~30-40 hours (DSMZ=ACC-960).
Derived from site: In situ; Extrahepatic bile duct; UBERON=UBERON_0003703.
Disease Hilar cholangiocarcinoma (NCIt: C36077)
Klatskin tumor (ORDO: Orphanet_99978)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_D4A6 ! CCArly CAF
Sex of cell Female
Age at sampling 72Y
Category Cancer cell line
STR profile Source(s): DSMZ=ACC-960

Markers:
AmelogeninX
CSF1PO11
D2S133817,25
D3S135816
D5S81810,12
D7S82010,13
D8S117913
D13S3178,9
D16S53911,14
D18S5116
D19S43312
D21S1128,29
FGA20,22
Penta D11
Penta E12,13
TH018,9.3
TPOX8,10
vWA16,19

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Publications

PubMed=36980644; DOI=10.3390/cancers15061757; PMCID=PMC10046314
Schrom S., Kleinegger F., Anders I., Hebesberger T., Karner C., Liesinger L., Birner-Gruenberger R., Renner W., Pichler M., Grillari-Voglauer R., Aigelsreiter A., Rinner B.
MUG CCArly: a novel autologous 3D cholangiocarcinoma model presents an increased angiogenic potential.
Cancers (Basel) 15:1757.1-1757.21(2023)

Cross-references
Cell line collections (Providers) DSMZ; ACC-960
Encyclopedic resources Wikidata; Q127382899
Entry history
Entry creation30-Jan-2024
Last entry update10-Sep-2024
Version number2