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Cellosaurus MDCK siat7e-expressing clone 1 (CVCL_D3W3)

[Text version]
Cell line name MDCK siat7e-expressing clone 1
Accession CVCL_D3W3
Resource Identification Initiative To cite this cell line use: MDCK siat7e-expressing clone 1 (RRID:CVCL_D3W3)
Comments Group: Vaccine production cell line.
Characteristics: Grows in suspension (PubMed=19706449).
Virology: Allows efficient influenza virus growth and hemagglutinin (HA) production (PubMed=19706449).
Transfected with: HGNC; 19342; ST6GALNAC5.
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Cell type: Epithelial cell of kidney; CL=CL_0002518.
Species of origin Canis lupus familiaris (Dog) (Canis familiaris) (NCBI Taxonomy: 9615)
Breed/subspecies: Cocker Spaniel.
Hierarchy Parent: CVCL_0422 (MDCK)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line

PubMed=19706449; DOI=10.1073/pnas.0905912106
Chu C., Lugovtsev V.Y., Golding H., Betenbaugh M.J., Shiloach J.
Conversion of MDCK cell line to suspension culture by transfecting with human siat7e gene and its application for influenza virus production.
Proc. Natl. Acad. Sci. U.S.A. 106:14802-14807(2009)

Entry history
Entry creation30-Jan-2024
Last entry update30-Jan-2024
Version number1