ID   MDCK siat7e-expressing clone 1
AC   CVCL_D3W3
DR   Wikidata; Q127382754
RX   PubMed=19706449;
CC   Group: Vaccine production cell line.
CC   Characteristics: Grows in suspension (PubMed=19706449).
CC   Virology: Allows efficient influenza virus growth and hemagglutinin (HA) production (PubMed=19706449).
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:19342; ST6GALNAC5.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
CC   Cell type: Epithelial cell of kidney; CL=CL_0002518.
CC   Breed/subspecies: Cocker Spaniel; VBO=VBO_0200372.
OX   NCBI_TaxID=9615; ! Canis lupus familiaris (Dog)
HI   CVCL_0422 ! MDCK
SX   Female
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 30-01-24; Last updated: 19-12-24; Version: 3
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RX   PubMed=19706449; DOI=10.1073/pnas.0905912106; PMCID=PMC2728112;
RA   Chu C., Lugovtsev V.Y., Golding H., Betenbaugh M.J., Shiloach J.;
RT   "Conversion of MDCK cell line to suspension culture by transfecting
RT   with human siat7e gene and its application for influenza virus
RT   production.";
RL   Proc. Natl. Acad. Sci. U.S.A. 106:14802-14807(2009).
//