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Cellosaurus LN229/CD133 (CVCL_D2RW)

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Cell line name LN229/CD133
Accession CVCL_D2RW
Resource Identification Initiative To cite this cell line use: LN229/CD133 (RRID:CVCL_D2RW)
Comments Population: Caucasian.
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:9454; PROM1 (Note=With a N-terminal GVAMPGAEDDVV = PA-tag and a C-terminal with a C-terminal DMVNPGLEDRIE = RAP-tag and GDGMVPPGIEDK = MAP-tag).
Derived from site: In situ; Brain, right frontal parieto-occipital cortex.
Sequence variations
  • Mutation; HGNC; HGNC:6597; LIFR; Simple; p.Pro1060Ala (c.3178C>G); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9811; RAD21; Simple; p.Gln132Ter (c.394C>T); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro98Leu (c.293C>T); ClinVar=VCV000528236; Zygosity=Homozygous (from parent cell line).
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0393 (LN-229)
Sex of cell Female
Age at sampling 60Y
Category Cancer cell line
Publications

PubMed=28910211; DOI=10.1089/mab.2017.0031; PMCID=PMC6975129
Shunsuke Itai, Yuki Fujii, Takuro Nakamura, Yao-Wen Chang, Miyuki Yanaka, Noriko Saidoh, Saori Handa, Hiroyoshi Suzuki, Hiroyuki Harada, Shinji Yamada, Mika Kato Kaneko, Yukinari Kato;
Establishment of CMab-43, a sensitive and specific anti-CD133 monoclonal antibody, for immunohistochemistry.
Monoclon. Antib. Immunodiagn. Immunother. 36:231-235(2017)

Cross-references
Encyclopedic resources Wikidata; Q127382598
Entry history
Entry creation30-Jan-2024
Last entry update14-Aug-2025
Version number4