ID   LN229/CD133
AC   CVCL_D2RW
DR   Wikidata; Q127382598
RX   PubMed=28910211;
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; HGNC:6597; LIFR; Simple; p.Pro1060Ala (c.3178C>G); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:9811; RAD21; Simple; p.Gln132Ter (c.394C>T); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro98Leu (c.293C>T); ClinVar=VCV000528236; Zygosity=Homozygous (from parent cell line).
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:9454; PROM1 (Note=With a N-terminal GVAMPGAEDDVV = PA-tag and a C-terminal with a C-terminal DMVNPGLEDRIE = RAP-tag and GDGMVPPGIEDK = MAP-tag).
CC   Derived from site: In situ; Brain, right frontal parieto-occipital cortex.
DI   NCIt; C3058; Glioblastoma
DI   ORDO; Orphanet_360; Glioblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0393 ! LN-229
SX   Female
AG   60Y
CA   Cancer cell line
DT   Created: 30-01-24; Last updated: 19-12-24; Version: 3
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RX   PubMed=28910211; DOI=10.1089/mab.2017.0031; PMCID=PMC6975129;
RA   Itai S., Fujii Y., Nakamura T., Chang Y.-W., Yanaka M., Saidoh N.,
RA   Handa S., Suzuki H., Harada H., Yamada S., Kaneko M.K., Kato Y.;
RT   "Establishment of CMab-43, a sensitive and specific anti-CD133
RT   monoclonal antibody, for immunohistochemistry.";
RL   Monoclon. Antib. Immunodiagn. Immunother. 36:231-235(2017).
//